Author: Kumar, Satyendra; Arankalle, Vidya A.
Title: Intracranial Administration of P Gene siRNA Protects Mice from Lethal Chandipura Virus Encephalitis Document date: 2010_1_7
ID: 1mzq227n_25
Snippet: BALB/c mice aged 4-6 wks were used for all in vivo experiments. These experiments were done in a biosafety level 2 animal facility at the NIV and were approved by the Institutional Animal Ethics Committee (IAEC) for animal experimentations. Mice were inoculated intracranially (ic) with CHPV. For experiments using siRNA, siRNAs were complexed with HiPerfect TM (QIAGEN, Valencia CA) according to the manufacturer's instructions and were administered.....
Document: BALB/c mice aged 4-6 wks were used for all in vivo experiments. These experiments were done in a biosafety level 2 animal facility at the NIV and were approved by the Institutional Animal Ethics Committee (IAEC) for animal experimentations. Mice were inoculated intracranially (ic) with CHPV. For experiments using siRNA, siRNAs were complexed with HiPerfect TM (QIAGEN, Valencia CA) according to the manufacturer's instructions and were administered at the same site once simultaneously or at different intervals.
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