Author: Lee, Yu-Ching; Tsai, Keng-Chang; Leu, Sy-Jye; Wang, Tuan-Jen; Liu, Chia-Yu; Yang, Yi-Yuan
Title: Isolation, Characterization, and Molecular Modeling of a Rheumatoid Factor from a Hepatitis C Virus Infected Patient with Sjögren's Syndrome Document date: 2013_12_30
ID: 0zsn4lu3_20
Snippet: Homology model of RFL11 was generated by MODELER v.9.4 program in Discovery Studio v.3.5 (Accelrys Software Inc., San Diego, CA, USA) using the crystallographic structures of the light chain of RF61 (PDB id: 2J6E) and the heavy chain of the antibody (PDB id: 3H0T) as structural templates. Both structures have good resolution and belong to Homo sapiens. Thus, the interface of the template structure between L chain and H chain of RF61 was employed .....
Document: Homology model of RFL11 was generated by MODELER v.9.4 program in Discovery Studio v.3.5 (Accelrys Software Inc., San Diego, CA, USA) using the crystallographic structures of the light chain of RF61 (PDB id: 2J6E) and the heavy chain of the antibody (PDB id: 3H0T) as structural templates. Both structures have good resolution and belong to Homo sapiens. Thus, the interface of the template structure between L chain and H chain of RF61 was employed to build the light chain-heavy chain interface of RFL11 scFv model.
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