Author: Suthar, Mehul S.; Ma, Daphne Y.; Thomas, Sunil; Lund, Jennifer M.; Zhang, Nu; Daffis, Stephane; Rudensky, Alexander Y.; Bevan, Michael J.; Clark, Edward A.; Kaja, Murali-Krishna; Diamond, Michael S.; Gale, Michael
Title: IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity Document date: 2010_2_5
ID: 094d0rn6_24
Snippet: We further analyzed the lymphocyte composition of the spleen on day 6 after WNV infection (Fig 7) . Gross pathologic analysis revealed that WNV infection of IPS-1 2/2 mice results in massive splenomegaly whereas infection of wild type mice induces only a slight increase in spleen size (Fig 7A) . Cell analysis revealed increased numbers of total lymphocytes in the spleens of infected IPS-1 2/2 mice as compared to wild type mice (Fig 7B) ......
Document: We further analyzed the lymphocyte composition of the spleen on day 6 after WNV infection (Fig 7) . Gross pathologic analysis revealed that WNV infection of IPS-1 2/2 mice results in massive splenomegaly whereas infection of wild type mice induces only a slight increase in spleen size (Fig 7A) . Cell analysis revealed increased numbers of total lymphocytes in the spleens of infected IPS-1 2/2 mice as compared to wild type mice (Fig 7B) .
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