Author: Zhang, Qingshui; Cao, Yanxin; Wang, Jun; Fu, Guanghua; Sun, Mengxu; Zhang, Lijiao; Meng, Li; Cui, Guolin; Huang, Yu; Hu, Xueying; Su, Jingliang
Title: Isolation and characterization of an astrovirus causing fatal visceral gout in domestic goslings Document date: 2018_4_19
ID: 1k5jucae_18
Snippet: Orally inoculation of goslings with the isolate resulted in depression of 4 birds from 5 to 8 dpi. One gosling died at 7 dpi with evident urate deposition on the surfaces of heart and liver at necropsy. Another severely ill bird was killed humanely at 8 dpi for animal welfare reasons. Viral RNA was detected by RT-PCR in the cloacal swabs from 4 dpi (Fig. S3) and growth depression was noticed in this group (Fig. S5) . For the goslings infected by .....
Document: Orally inoculation of goslings with the isolate resulted in depression of 4 birds from 5 to 8 dpi. One gosling died at 7 dpi with evident urate deposition on the surfaces of heart and liver at necropsy. Another severely ill bird was killed humanely at 8 dpi for animal welfare reasons. Viral RNA was detected by RT-PCR in the cloacal swabs from 4 dpi (Fig. S3) and growth depression was noticed in this group (Fig. S5) . For the goslings infected by intranasal inoculation, no death occurred in the group, but virus shedding and growth depress was observed (Fig. S4 & S5) . These results indicated that the isolate might infect goslings via oral and nasal routes, further demonstrating the infectivity of the isolate.
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