Selected article for: "heavy chain and light chain cdr"

Author: Lee, Yu-Ching; Tsai, Keng-Chang; Leu, Sy-Jye; Wang, Tuan-Jen; Liu, Chia-Yu; Yang, Yi-Yuan
Title: Isolation, Characterization, and Molecular Modeling of a Rheumatoid Factor from a Hepatitis C Virus Infected Patient with Sjögren's Syndrome
  • Document date: 2013_12_30
  • ID: 0zsn4lu3_31
    Snippet: Compared to sequences in the CDR domains of RF61 RF molecule, light chain shows the most similarity except CDR3. RFL11 has replacement of Aspartate (D) and Serine (S) with Glutamine (Q) and Asparagine (N). For heavy chain, significant dissimilarity on CDR was shown on CDR2 and CDR3 with additional residues. Besides, the framework of RFL11 to 2J6E was high similarity (Figure 6 )......
    Document: Compared to sequences in the CDR domains of RF61 RF molecule, light chain shows the most similarity except CDR3. RFL11 has replacement of Aspartate (D) and Serine (S) with Glutamine (Q) and Asparagine (N). For heavy chain, significant dissimilarity on CDR was shown on CDR2 and CDR3 with additional residues. Besides, the framework of RFL11 to 2J6E was high similarity (Figure 6 ).

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