Author: Fallahi, Poupak; Ferrari, Silvia Martina; Politti, Ugo; Giuggioli, Dilia; Ferri, Clodoveo; Antonelli, Alessandro
Title: Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection Document date: 2014_10_13
ID: 0go1vl9q_16
Snippet: Autoimmunity. In a first study, Tran et al. report two cases of Hashimoto's thyroiditis associated with chronic active HCV infection, suggesting that HCV infection might be involved in the appearance of AT [34, 35] . The prevalence of HCV infection in patients with different thyroid disorders has been evaluated by several studies with conflicting results. Duclos-Vallée et al. evaluated the prevalence of HCV infection in 200 patients with thyroid.....
Document: Autoimmunity. In a first study, Tran et al. report two cases of Hashimoto's thyroiditis associated with chronic active HCV infection, suggesting that HCV infection might be involved in the appearance of AT [34, 35] . The prevalence of HCV infection in patients with different thyroid disorders has been evaluated by several studies with conflicting results. Duclos-Vallée et al. evaluated the prevalence of HCV infection in 200 patients with thyroid diseases; among 50 patients with simple goiter, none were anti-HCV-positive; among 50 individuals with goiter, 2 were positive; among 5 individuals with myxedema, 2 were positive; among 50 patients with Hashimoto's thyroiditis, 12 were positive. These results suggested that HCV infection might be associated with AT [36] . Recently, Yang et al. compared 462 persons with positive AbTPO and/or AbTg to 360 persons with antibody negativity and no difference in the prevalence of anti-HCV positivity between the 2 groups (1.3% versus 0.53%; > 0.05) was found [37] . In a study conducted by Marconcini et al., 66 HCV+ patients were evaluated and AbTPOs were detected in 4/54 (7.4%) of the patients, whereas AbTgs were detected in none of the patients (0/48) [38] .
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