Selected article for: "gene expression and necrosis factor"
Author: Fallahi, Poupak; Ferrari, Silvia Martina; Politti, Ugo; Giuggioli, Dilia; Ferri, Clodoveo; Antonelli, Alessandro
Title: Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection
  • Document date: 2014_10_13
    • ID: 0go1vl9q_38
    Snippet: On the abovementioned bases, it has been speculated that HCV thyroid infection may act by upregulating CXCL10 gene expression and secretion in thyrocytes recruiting Th1 lymphocytes that secrete IFN-and tumor necrosis factor-(TNF-) . These cytokines induce CXCL10 secretion by thyrocytes, thus perpetuating the immune cascade, which may lead to the appearance of AITD in genetically predisposed subjects [111] ( Figure 1) ......
    Document: On the abovementioned bases, it has been speculated that HCV thyroid infection may act by upregulating CXCL10 gene expression and secretion in thyrocytes recruiting Th1 lymphocytes that secrete IFN-and tumor necrosis factor-(TNF-) . These cytokines induce CXCL10 secretion by thyrocytes, thus perpetuating the immune cascade, which may lead to the appearance of AITD in genetically predisposed subjects [111] ( Figure 1) .

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