Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection

Fallahi, Poupak; Ferrari, Silvia Martina; Politti, Ugo; Giuggioli, Dilia; Ferri, Clodoveo; Antonelli, Alessandro

In conclusion, the abovementioned results show a high prevalence of AITD in patients with CHC infection. The presence of a higher risk of AT in female gender, increased circulating levels of AbTPOs, and increased risk of hypothyroidism in female gender and AbTPO-positive subjects characterized the pattern of thyroid disorders observed in HCV infection. In HCV patients with thyroid cancer, thyroidectomy is required and, if appropriate, radioiodine treatment. Patients with HCV infection with AITD where nodules occurred and in fine needle aspiration biopsy without neoplastic processes do require careful observation.