Author: Cori, Anne; Donnelly, Christl A.; Dorigatti, Ilaria; Ferguson, Neil M.; Fraser, Christophe; Garske, Tini; Jombart, Thibaut; Nedjati-Gilani, Gemma; Nouvellet, Pierre; Riley, Steven; Van Kerkhove, Maria D.; Mills, Harriet L.; Blake, Isobel M.
Title: Key data for outbreak evaluation: building on the Ebola experience Document date: 2017_5_26
ID: 12t247bn_9
Snippet: The severity of a pathogen is often characterized by the case fatality ratio (CFR), the proportion of cases who die as a result of their infection. Estimating the CFR during an outbreak can be challenging due to inconsistent case definitions, incomplete case reporting and right-censoring of data [27] [28] [29] . In particular, it is critical to know the proportion of cases for whom clinical outcome is unknown or has not been recorded, which is ty.....
Document: The severity of a pathogen is often characterized by the case fatality ratio (CFR), the proportion of cases who die as a result of their infection. Estimating the CFR during an outbreak can be challenging due to inconsistent case definitions, incomplete case reporting and right-censoring of data [27] [28] [29] . In particular, it is critical to know the proportion of cases for whom clinical outcome is unknown or has not been recorded, which is typically easier to assess using detailed case data rather than aggregated case counts [27] . The CFR may differ across populations (e.g. age, space, treatment); quantifying Box 1. Recommendations for collecting and using data for outbreak response.
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