Author: Xianfei Zeng; Hongyan Fan; Dongxue Lu; Fang Huang; Xi Meng; Zhuo Li; Mei Tang; Jing Zhang; Nannan Liu; Zhixin Liu; Jingya Zhao; Wen Yin; Qunxing An; Xijing Zhang; Xingbin Hu
Title: Association between ABO blood groups and clinical outcome of coronavirus disease 2019: Evidence from two cohorts Document date: 2020_4_17
ID: idd8uq9h_60
Snippet: Apart from the regular expression on the red blood cell surface, blood group antigens are also widely distributed on various cells and sometimes in body fluids, including respiratory epithelial cells and alveolar epithelial cells. We believe that the genetic susceptibility of blood type glycophorin may function via receptor-mediated affinity binding, especially in the invasion mechanism. Blood group antigens are proven to be effective receptors f.....
Document: Apart from the regular expression on the red blood cell surface, blood group antigens are also widely distributed on various cells and sometimes in body fluids, including respiratory epithelial cells and alveolar epithelial cells. We believe that the genetic susceptibility of blood type glycophorin may function via receptor-mediated affinity binding, especially in the invasion mechanism. Blood group antigens are proven to be effective receptors for several infectious microorganisms [31] . The specific ABO glycan antigen receptors binding to the virus spike (S) protein may support virus entry during infection.
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