Author: Barker, Emily N.; Stranieri, Angelica; Helps, Chris R.; Porter, Emily L.; Davidson, Andrew D.; Day, Michael J.; Knowles, Toby; Kipar, Anja; Tasker, Séverine
Title: Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis Document date: 2017_10_5
ID: 08b0g46x_29
Snippet: Samples were available from 127 cats ( Figure 2 ); for 102 of these, a definitive diagnosis was achieved (full details of the samples and results-Additional file 1): 57 cats with FIP; and 45 cats without FIP. Of the 25 cats excluded, five had no tissue samples collected into formalin, six had no tissue samples collected into RNAlater; and 14 only had limited tissue samples collected into formalin such that FIP could not be definitively diagnosed .....
Document: Samples were available from 127 cats ( Figure 2 ); for 102 of these, a definitive diagnosis was achieved (full details of the samples and results-Additional file 1): 57 cats with FIP; and 45 cats without FIP. Of the 25 cats excluded, five had no tissue samples collected into formalin, six had no tissue samples collected into RNAlater; and 14 only had limited tissue samples collected into formalin such that FIP could not be definitively diagnosed or excluded. Of the cats without FIP the reason for euthanasia and postmortem diagnosis comprised: neoplasia in 16; inflammatory/infectious (not FIP) disease in 15; metabolic disease in four; cardiac in 1; immune-mediated in 2; miscellaneous in 6; and on behavioural grounds in 1.
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