Author: Mathieu, Cyrille; Guillaume, Vanessa; Sabine, Amélie; Ong, Kien Chai; Wong, Kum Thong; Legras-Lachuer, Catherine; Horvat, Branka
Title: Lethal Nipah Virus Infection Induces Rapid Overexpression of CXCL10 Document date: 2012_2_29
ID: 0d3vy87b_14
Snippet: Although expression of IFN alpha and beta was shown to be inhibited in human cell lines after NiV infection [20] , human primary endothelial cells seem to be resistant to this inhibition [21] . Our study demonstrated that a few other members of interferon type I pathway, including MxA, RIGI, 2959-OAS 1 and 2, are highly expressed early after NiV infection, suggesting a functional interferon pathway in NiV-infected human endothelial cells......
Document: Although expression of IFN alpha and beta was shown to be inhibited in human cell lines after NiV infection [20] , human primary endothelial cells seem to be resistant to this inhibition [21] . Our study demonstrated that a few other members of interferon type I pathway, including MxA, RIGI, 2959-OAS 1 and 2, are highly expressed early after NiV infection, suggesting a functional interferon pathway in NiV-infected human endothelial cells.
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