Author: Cori, Anne; Donnelly, Christl A.; Dorigatti, Ilaria; Ferguson, Neil M.; Fraser, Christophe; Garske, Tini; Jombart, Thibaut; Nedjati-Gilani, Gemma; Nouvellet, Pierre; Riley, Steven; Van Kerkhove, Maria D.; Mills, Harriet L.; Blake, Isobel M.
Title: Key data for outbreak evaluation: building on the Ebola experience Document date: 2017_5_26
ID: 12t247bn_45
Snippet: Studies of transmission in well-defined, small settings such as households are useful to quantify asymptomatic transmission, infectivity over time and the serial interval as they capture explicitly the number and timing of secondary cases. Additionally, these studies can estimate the secondary attack rate (the proportion of contacts of a case who become infected within one incubation period), which can be used to characterize heterogeneities in t.....
Document: Studies of transmission in well-defined, small settings such as households are useful to quantify asymptomatic transmission, infectivity over time and the serial interval as they capture explicitly the number and timing of secondary cases. Additionally, these studies can estimate the secondary attack rate (the proportion of contacts of a case who become infected within one incubation period), which can be used to characterize heterogeneities in transmission of different groups [59] . Estimates of the secondary attack rate have been obtained for the West African Ebola epidemic by reconstructing household data based on information reported by cases, in particular, as part of contact-tracing activities [86, 87] .
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