Author: Allemandou, Aude; Grasland, Béatrice; Hernandez-Nignol, Anne-Cécile; Kéranflec'h, André; Cariolet, Roland; Jestin, André
Title: Modification of PCV-2 virulence by substitution of the genogroup motif of the capsid protein Document date: 2011_3_24
ID: 1fl0we2a_3
Snippet: The PCV-2 capsid protein is composed of 233 amino acids and is about 30kDa [8] . Three-dimensional maps from electron micrographs have shown that PCV-2 has an icosahedral virus surface containing 60 capsid proteins arranged in 12 pentamers and have a diameter of 20 nm [16] . The capsid protein is the most variable protein in the PCV-2 (91 to 100% of identity in nucleic acids versus 98 to 100% for the Rep). It is the main antigenic determinant of .....
Document: The PCV-2 capsid protein is composed of 233 amino acids and is about 30kDa [8] . Three-dimensional maps from electron micrographs have shown that PCV-2 has an icosahedral virus surface containing 60 capsid proteins arranged in 12 pentamers and have a diameter of 20 nm [16] . The capsid protein is the most variable protein in the PCV-2 (91 to 100% of identity in nucleic acids versus 98 to 100% for the Rep). It is the main antigenic determinant of PCV-2 and contains four linear B-cell epitopes. These four immunodomains are enclosed between amino acids 65 to 87, 113 to 139, 169 to 183 and the last one between amino acids 230 and 234 [17, 18] , leading to this protein being used for vaccine development.
Search related documents:
Co phrase search for related documents- amino acid and capsid protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
- amino acid and electron micrograph: 1
- amino acid and nucleic acid: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70
- amino acid and nucleic acid identity: 1, 2
- amino acid and vaccine development: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- amino acid and vaccine development protein: 1, 2, 3, 4, 5, 6, 7, 8, 9
- amino acid and variable protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- amino acid and virus surface: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53
- antigenic determinant and main antigenic determinant: 1, 2, 3
- antigenic determinant and vaccine development: 1
- antigenic determinant and virus surface: 1, 2, 3
- capsid protein and nucleic acid: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- capsid protein and vaccine development: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33
- capsid protein and vaccine development protein: 1, 2, 3, 4
- capsid protein and virus surface: 1, 2, 3, 4, 5, 6, 7, 8
- electron micrograph and virus surface: 1
- nucleic acid and vaccine development: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48
- nucleic acid and vaccine development protein: 1, 2, 3, 4, 5
- nucleic acid and variable protein: 1
Co phrase search for related documents, hyperlinks ordered by date