Selected article for: "causative agent and Lassa virus"
Author: Warner, Nikole L.; Jokinen, Jenny D.; Beier, Juliane I.; Sokoloski, Kevin J.; Lukashevich, Igor S.
Title: Mammarenaviral Infection Is Dependent on Directional Exposure to and Release from Polarized Intestinal Epithelia
  • Document date: 2018_2_10
    • ID: 1t8jmunt_1
    Snippet: Arenaviruses are enveloped viruses that have a single-stranded, bisegmented, ambisense RNA genome. The Large (L) segment, encodes the matrix protein (Z), and the RNA dependent RNA polymerase [1] . The Small (S) segment, encodes the nucleoproteins (NPs) and glycoproteins (GP) [1] . Initially, arenaviruses were thought to only infect mammals; however, recently arenaviruses have been identified as the causative agent of inclusion body disease in the.....
    Document: Arenaviruses are enveloped viruses that have a single-stranded, bisegmented, ambisense RNA genome. The Large (L) segment, encodes the matrix protein (Z), and the RNA dependent RNA polymerase [1] . The Small (S) segment, encodes the nucleoproteins (NPs) and glycoproteins (GP) [1] . Initially, arenaviruses were thought to only infect mammals; however, recently arenaviruses have been identified as the causative agent of inclusion body disease in the boid family of snakes [2] . Hence, Arenaviruses have been separated into two genera on the basis of their natural reservoir hosts; mammarenavirus, which infect mammalian hosts, and reptarenavirus which infect reptilian host species [3] . Among the mammarenavirus genera, there is further subdivision into the Old World (OW) LCMV-Lassa virus complex and New World (NW), Tacaribe virus complex [3, 4] .

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