Author: Mathieu, Cyrille; Guillaume, Vanessa; Sabine, Amélie; Ong, Kien Chai; Wong, Kum Thong; Legras-Lachuer, Catherine; Horvat, Branka
Title: Lethal Nipah Virus Infection Induces Rapid Overexpression of CXCL10 Document date: 2012_2_29
ID: 0d3vy87b_1
Snippet: Nipah virus (NiV) is a recently emerged zoonotic pathogen of the family Paramyxoviridae that is distinguished by its ability to cause fatal disease in both animals and humans. NiV along with Hendra virus (HeV) comprise the new genus Henipavirus (reviewed in [1] ). NiV was first identified during an outbreak of severe encephalitis in Malaysia and Singapore in 1998-99, with pigs serving as the intermediate amplifying host [2] . Since 1998 NiV has c.....
Document: Nipah virus (NiV) is a recently emerged zoonotic pathogen of the family Paramyxoviridae that is distinguished by its ability to cause fatal disease in both animals and humans. NiV along with Hendra virus (HeV) comprise the new genus Henipavirus (reviewed in [1] ). NiV was first identified during an outbreak of severe encephalitis in Malaysia and Singapore in 1998-99, with pigs serving as the intermediate amplifying host [2] . Since 1998 NiV has caused regular outbreaks, primarily in Bangladesh and India, with the most recent occurrences at the beginning of 2011 [3] . In the majority of subsequent spillover events, the mortality rate among humans has been higher (,75%) along with evidence of multiple rounds of person-to-person transmission [4, 5, 6] .
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