Author: Barker, Emily N.; Stranieri, Angelica; Helps, Chris R.; Porter, Emily L.; Davidson, Andrew D.; Day, Michael J.; Knowles, Toby; Kipar, Anja; Tasker, Séverine
Title: Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis Document date: 2017_10_5
ID: 08b0g46x_60
Snippet: The reference-standard for diagnosis of FIP was considered identification of FCoV antigen by immunohistochemistry in at least one tissue in association with appropriate histopathological changes, and cats were considered "without FIP" where FIP was excluded as a diagnosis. a As some positive samples without histopathological data were not subjected to sequencing, only those samples with histopathological data available were included in these calc.....
Document: The reference-standard for diagnosis of FIP was considered identification of FCoV antigen by immunohistochemistry in at least one tissue in association with appropriate histopathological changes, and cats were considered "without FIP" where FIP was excluded as a diagnosis. a As some positive samples without histopathological data were not subjected to sequencing, only those samples with histopathological data available were included in these calculations. b RT-qPCR in combination with spike protein sequence characterisation FCoV. c One sample lost from analysis.
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