Author: Yang, Liu; Du, Xing; Liu, Lu; Cao, Qiuyu; Pan, Zengxiang; Li, Qifa
Title: miR-1306 Mediates the Feedback Regulation of the TGF-ß/SMAD Signaling Pathway in Granulosa Cells Document date: 2019_3_31
ID: 16qix4ab_2
Snippet: The mutational inactivation of TGFBR2 can inhibit TGF-β/SMAD signaling pathway activity and its tumor-suppressing ability, thereby promoting colon cancer [7] . Besides, down-regulation of TGFBR2 by using TGFBR2-specific small interfering RNAs (siRNAs) or a small-molecule inhibitor ablates the TGF-β signal-mediated process [8, 9] ......
Document: The mutational inactivation of TGFBR2 can inhibit TGF-β/SMAD signaling pathway activity and its tumor-suppressing ability, thereby promoting colon cancer [7] . Besides, down-regulation of TGFBR2 by using TGFBR2-specific small interfering RNAs (siRNAs) or a small-molecule inhibitor ablates the TGF-β signal-mediated process [8, 9] .
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