Selected article for: "expression level and significantly decrease"
Author: Yang, Liu; Du, Xing; Liu, Lu; Cao, Qiuyu; Pan, Zengxiang; Li, Qifa
Title: miR-1306 Mediates the Feedback Regulation of the TGF-ß/SMAD Signaling Pathway in Granulosa Cells
  • Document date: 2019_3_31
    • ID: 16qix4ab_35
    Snippet: Based on the KEGG analysis results revealing that miR-1306 may participate in apoptosis, we further investigated its role in apoptosis in porcine GCs. FACS assay showed that overexpression of miR-1306 significantly improved the GC apoptosis rate (Figure 3A) , while a decrease in miR-1306 levels reduced it ( Figure 3B ). This suggests that miR-1306 can promote apoptosis of porcine GCs. Further, studies have shown that GC apoptosis is associated wi.....
    Document: Based on the KEGG analysis results revealing that miR-1306 may participate in apoptosis, we further investigated its role in apoptosis in porcine GCs. FACS assay showed that overexpression of miR-1306 significantly improved the GC apoptosis rate (Figure 3A) , while a decrease in miR-1306 levels reduced it ( Figure 3B ). This suggests that miR-1306 can promote apoptosis of porcine GCs. Further, studies have shown that GC apoptosis is associated with follicular atresia. Therefore, miR-1306 level in follicles during follicular atresia of porcine ovary was measured. We discovered that the expression level of miR-1306 was remarkably increased during follicular atresia (Supplementary

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