Author: Ojosnegros, Samuel; Beerenwinkel, Niko
Title: Models of RNA virus evolution and their roles in vaccine design Document date: 2010_11_3
ID: 0q928h3b_45
Snippet: After several attempts to obtain a protective vaccine against HIV, current efforts have shifted toward developing therapeutic vaccines which help to control infection. A vaccine that elicits an incomplete response may be sufficient to keep viral load in controllable levels. The vaccine would not prevent infection by HIV, but it would delay or prevent the progression to AIDS, the final stage of the disease [137] . The reduction in viral load would.....
Document: After several attempts to obtain a protective vaccine against HIV, current efforts have shifted toward developing therapeutic vaccines which help to control infection. A vaccine that elicits an incomplete response may be sufficient to keep viral load in controllable levels. The vaccine would not prevent infection by HIV, but it would delay or prevent the progression to AIDS, the final stage of the disease [137] . The reduction in viral load would also reduce the number of secondary transmissions of the infection, because the efficiency of transmission depends on viral load levels.
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