Author: Ojosnegros, Samuel; Beerenwinkel, Niko
Title: Models of RNA virus evolution and their roles in vaccine design Document date: 2010_11_3
ID: 0q928h3b_23
Snippet: Not only selection, but also neutral genetic drift seems to play an important role in the evolution of influenza virus. Both evolutionary forces, termed antigenic drift and antigenic shift, have been observed in human hosts over the last century. Antigenic drift refers to neutral evolutionary changes accumulating over time, whereas antigenic shift involves a change in genetic and serological properties of the virus due to new HA or NA subtypes......
Document: Not only selection, but also neutral genetic drift seems to play an important role in the evolution of influenza virus. Both evolutionary forces, termed antigenic drift and antigenic shift, have been observed in human hosts over the last century. Antigenic drift refers to neutral evolutionary changes accumulating over time, whereas antigenic shift involves a change in genetic and serological properties of the virus due to new HA or NA subtypes.
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