Author: Ojosnegros, Samuel; Beerenwinkel, Niko
Title: Models of RNA virus evolution and their roles in vaccine design Document date: 2010_11_3
ID: 0q928h3b_54
Snippet: Individual viruses inside the quasispecies can display very different degrees of virulence. This trait is measured as the cell killing capacity, when considering cell culture experiments, and as the host morbidity or mortality, when focusing on whole-organism pathology [158, 159] . Replicative fitness is also highly variable among viruses of the same quasispecies, and in general, not directly correlated to virulence [158] . Understanding the evol.....
Document: Individual viruses inside the quasispecies can display very different degrees of virulence. This trait is measured as the cell killing capacity, when considering cell culture experiments, and as the host morbidity or mortality, when focusing on whole-organism pathology [158, 159] . Replicative fitness is also highly variable among viruses of the same quasispecies, and in general, not directly correlated to virulence [158] . Understanding the evolution of these two viral traits is fundamental to understanding and controlling the spread of viral diseases and to the design of LAVs.
Search related documents:
Co phrase search for related documents- cell culture and individual virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- cell culture and lav design: 1, 2
- cell culture and replicative fitness: 1, 2, 3, 4
- cell culture and viral disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47
- cell culture and viral disease spread: 1
- cell culture and virulence correlate: 1, 2
- different degree and host morbidity: 1
- different degree and individual virus: 1
- different degree and mortality host morbidity: 1
- host morbidity and mortality host morbidity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26
- host morbidity and viral disease: 1, 2, 3
- individual virus and viral disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- individual virus and viral disease spread: 1, 2
Co phrase search for related documents, hyperlinks ordered by date