Author: Hsu, Shih-Hsien; Yeh, Ming-Lun; Wang, Shen-Nien
Title: New Insights in Recurrent HCV Infection after Liver Transplantation Document date: 2013_4_23
ID: 0hbeso65_36
Snippet: Cd81, a ubiquitously expressed 25 kDa tetraspanin, has been demonstrated to interact with the soluble truncated form of HCV E2 [89] . Its large extracellular loop (LEL) seems to play a critical role in this interaction process. Moreover, studies have identified several amino acid residues throughout the CD81 LEL and HCV E2, which might be crucial for E2-CD81 binding [90, 91] . SR-BI, an 82 kDa glycoprotein with a large extracellular loop, is high.....
Document: Cd81, a ubiquitously expressed 25 kDa tetraspanin, has been demonstrated to interact with the soluble truncated form of HCV E2 [89] . Its large extracellular loop (LEL) seems to play a critical role in this interaction process. Moreover, studies have identified several amino acid residues throughout the CD81 LEL and HCV E2, which might be crucial for E2-CD81 binding [90, 91] . SR-BI, an 82 kDa glycoprotein with a large extracellular loop, is highly expressed in the liver [92] .
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