Author: Stark, Caren J; Atreya, CD
Title: Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies Document date: 2005_4_15
ID: 0fitbwuv_31
Snippet: SARS-CoV clearly has pandemic potential. Although progress in SARS-CoV molecular and cell biology research has been remarkable, there remain clear limitations regarding vaccine development due to a lack of complete understanding in the areas of animal models of the disease as well as host immune responses to the evolving molecular diversity of this newly emerged human virus. Caution is warranted when utilizing experimental data originating from o.....
Document: SARS-CoV clearly has pandemic potential. Although progress in SARS-CoV molecular and cell biology research has been remarkable, there remain clear limitations regarding vaccine development due to a lack of complete understanding in the areas of animal models of the disease as well as host immune responses to the evolving molecular diversity of this newly emerged human virus. Caution is warranted when utilizing experimental data originating from one SARS-CoV strain infection in one animal species or cell line in the development of a human vaccine. The rapid development of an effective SARS-CoV vaccine depends upon continuing basic research.
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