Selected article for: "control origin and genome sequencing"
Author: Lau, Susanna K. P.; Wong, Antonio C. P.; Lau, Terrence C. K.; Woo, Patrick C. Y.
Title: Molecular Evolution of MERS Coronavirus: Dromedaries as a Recent Intermediate Host or Long-Time Animal Reservoir?
  • Document date: 2017_10_16
    • ID: 1sq2uvur_5
    Snippet: Up to March 2017, a total of more than 200 complete genome sequences of MERS-CoV are available in GenBank, with around half of them from MERS-CoVs found in human and the other half from MERS-CoVs in dromedaries. Based on our previous studies on genome sequencing and phylogenetic analysis of MERS-CoVs from dromedaries of the United Arab Emirates (UAE), we observed that diverse MERS-CoV strains were circulating in these dromedaries, supporting a po.....
    Document: Up to March 2017, a total of more than 200 complete genome sequences of MERS-CoV are available in GenBank, with around half of them from MERS-CoVs found in human and the other half from MERS-CoVs in dromedaries. Based on our previous studies on genome sequencing and phylogenetic analysis of MERS-CoVs from dromedaries of the United Arab Emirates (UAE), we observed that diverse MERS-CoV strains were circulating in these dromedaries, supporting a polyphyletic origin [13] . In this study, we analyzed the diversity and phylogeny of all the 219 human and dromedary MERS-CoV genome sequences in GenBank. Possible recombination events among the MERS-CoV strains were also detected. The implications of the results on the origin and control of MERS, and the role of dromedary camels in the evolution of MERS-CoV, are discussed.

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