Selected article for: "additional investigation and viral protein function"
Author: Zivcec, Marko; Scholte, Florine E. M.; Spiropoulou, Christina F.; Spengler, Jessica R.; Bergeron, Éric
Title: Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus
  • Document date: 2016_4_21
    • ID: 0a20s62q_46
    Snippet: Advancement in all the aforementioned areas should be complemented and supported by additional investigation into viral interactions with the tick-vector and host. Studies on the molecular aspects of CCHFV replication are almost exclusively focused on cell culture systems of mammalian cells. Since CCHFV establishes a persistent infection in ticks, CCHFV replication and viral protein function should be studied in ticks and tick cell lines [117, 11.....
    Document: Advancement in all the aforementioned areas should be complemented and supported by additional investigation into viral interactions with the tick-vector and host. Studies on the molecular aspects of CCHFV replication are almost exclusively focused on cell culture systems of mammalian cells. Since CCHFV establishes a persistent infection in ticks, CCHFV replication and viral protein function should be studied in ticks and tick cell lines [117, 118] . Additional research involving the tick vector and vector derived cells may aid in elucidating aspects of CCHFV that remain unclear in traditional mammalian cell based studies.

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