Selected article for: "admission body temperature and lopinavir ritonavir"
Author: Xudan Chen; Yang Zhang; Baoyi Zhu; Jianwen Zeng; Wenxin Hong; Xi He; Jingfeng Chen; Haipeng Zheng; Shuang Qiu; Ying Deng; Juliana Chan; Jian Wang
Title: Associations of clinical characteristics and antiviral drugs with viral RNA clearance in patients with COVID-19 in Guangzhou, China: a retrospective cohort study
  • Document date: 2020_4_14
    • ID: 9j4ese89_27
    Snippet: In this retrospective study, 89% of patients with COVID 19 achieved viral RNA clearance within 21 days. Time lag from illness onset to hospital admission, old age, disease severity, high body temperature, and corticosteroid use were associated with delayed clearance of viral RNA. The use of antiviral drugs (chloroquine, oseltamivir, arbidol, and lopinavir/ritonavir) had no benefit on such clearance. After adjusting for confounders, the use of lop.....
    Document: In this retrospective study, 89% of patients with COVID 19 achieved viral RNA clearance within 21 days. Time lag from illness onset to hospital admission, old age, disease severity, high body temperature, and corticosteroid use were associated with delayed clearance of viral RNA. The use of antiviral drugs (chloroquine, oseltamivir, arbidol, and lopinavir/ritonavir) had no benefit on such clearance. After adjusting for confounders, the use of lopinavir/ritonavir or the combination of two antiviral drugs tended to delay the clearance of viral RNA.

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