Selected article for: "control arm and POC testing"
Author: Andrews, Denise; Chetty, Yumela; Cooper, Ben S.; Virk, Manjinder; Glass, Stephen K; Letters, Andrew; Kelly, Philip A.; Sudhanva, Malur; Jeyaratnam, Dakshika
Title: Multiplex PCR point of care testing versus routine, laboratory-based testing in the treatment of adults with respiratory tract infections: a quasi-randomised study assessing impact on length of stay and antimicrobial use
  • Document date: 2017_10_10
    • ID: 1sdt9zz8_28
    Snippet: There was no evidence that the length of hospital stay, the primary endpoint, was reduced by POC testing. The median length of hospital stay was 79.6 h (IQR 41.9-188.9) in the control arm and 98.6 h (IQR 48.1-218.4) in the intervention arm. In the linear model (for log-transformed length of stay data, adjusting for potential confounders) the rapid test was associated with an absolute difference in the natural logarithm of the length of stay of 0......
    Document: There was no evidence that the length of hospital stay, the primary endpoint, was reduced by POC testing. The median length of hospital stay was 79.6 h (IQR 41.9-188.9) in the control arm and 98.6 h (IQR 48.1-218.4) in the intervention arm. In the linear model (for log-transformed length of stay data, adjusting for potential confounders) the rapid test was associated with an absolute difference in the natural logarithm of the length of stay of 0.108 (95% CI [−0.089, 0.305]; p = 0.28). This corresponds to an 11% (95% CI [−9%, 36%]) increase in length of stay associated with the rapid test arm. Six of 33 patients tested on the MAC in the control arm (18%) and 13 of 67 patients tested in the MAC in the intervention arm (19.4%) were discharged without admission to a hospital ward.

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