Atlas of ACE2 gene expression in mammals reveals novel insights in transmission of SARS-Cov-2

Kun Sun; Liuqi Gu; Li Ma; Yunfeng Duan

Transcriptome data for various mammalian tissues generated from 142 RNA-seq experiments (whole transcriptome shotgun sequencing) was collected from publicly available sources. Briefly, human data was from the GTEx (Genotype-Tissue Expression) project 14 , ENCODE (ENCyclopedia Of DNA Elements) project 15 , and . CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.30.015644 doi: bioRxiv preprint Frausto et al. 16 ; bat data was from Dong et al. 17 ; pangolin data was from Ma et al. 18 and Mohamed Yusoff et al. 19 ; cat data was from 99 Lives Cat Genome Sequencing Initiative project; dog data was from Hoeppner et al. 20 , Lindblad-Toh et al. 21 and Sudharsan et al. 22 ; ferret and rabbit data was from Chen et al. 23 ; hamster and goat data was from Fushan et al. 24 ; cow data was from Merkin et al. 25 ; and pig data was from Summers et al. 26 . Detailed information on accession numbers and tissues for each species was listed in Table S2 in Supplementary data.