Author: Colino, Clara I.; Millán, Carmen Gutiérrez; Lanao, José M.
Title: Nanoparticles for Signaling in Biodiagnosis and Treatment of Infectious Diseases Document date: 2018_5_31
ID: 1bxwb2hj_56
Snippet: Bacterial detection and killing in liquid-and solid-phase systems can also be achieved using surface-coatable NIR response fluorescent nanoparticles. Polydopamine (PdA) is a biomaterial with adhesive properties. Carbonized polydopamine (FDA) may be functionalized with polyethylenimine (PEI) to form fluorescent carbon nanoparticles (FDA:PEI). The cationic surface of these nanoparticles may bind to the anionic bacterial wall of Gram-positive and Gr.....
Document: Bacterial detection and killing in liquid-and solid-phase systems can also be achieved using surface-coatable NIR response fluorescent nanoparticles. Polydopamine (PdA) is a biomaterial with adhesive properties. Carbonized polydopamine (FDA) may be functionalized with polyethylenimine (PEI) to form fluorescent carbon nanoparticles (FDA:PEI). The cationic surface of these nanoparticles may bind to the anionic bacterial wall of Gram-positive and Gram-negative bacteria such as S. aureus or E. coli through changes in the fluorescent signal. In addition NIR irradiation of carbonized nanoparticles produces heat and kills the bacteria [64] .
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