Author: Bohmwald, Karen; Gálvez, Nicolás M. S.; Ríos, Mariana; Kalergis, Alexis M.
Title: Neurologic Alterations Due to Respiratory Virus Infections Document date: 2018_10_26
ID: 0rlotyz3_20
Snippet: Interestingly, as hRSV proteins were found in the hippocampus-a central zone where the cognitive and behavioral process takes place-alterations in the normal function were evaluated. Both hRSV-infected mice and rats were used for the evaluation of behavior and spatial learning, respectively (Espinoza et al., 2013) . Marble burying test was used to evaluate the mechanical digging behavior in rodents, and the data showed that a month after hRSV-inf.....
Document: Interestingly, as hRSV proteins were found in the hippocampus-a central zone where the cognitive and behavioral process takes place-alterations in the normal function were evaluated. Both hRSV-infected mice and rats were used for the evaluation of behavior and spatial learning, respectively (Espinoza et al., 2013) . Marble burying test was used to evaluate the mechanical digging behavior in rodents, and the data showed that a month after hRSV-infection, these mice exhibited an impairment in this behavior (Espinoza et al., 2013) . Moreover, hRSV-infected rats were submitted to the Morris Water Maze test-which evaluates spatial learning-a month after the infection. The data shows that hRSV-infected rats exhibited a delay in their learning capacities, when compared to the control group (Espinoza et al., 2013) . Considering these results, it is suggested that hRSV-infection causes behavioral and cognitive sequelae, that have not been described yet in patients.
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