Author: Colino, Clara I.; Millán, Carmen Gutiérrez; Lanao, José M.
Title: Nanoparticles for Signaling in Biodiagnosis and Treatment of Infectious Diseases Document date: 2018_5_31
ID: 1bxwb2hj_91
Snippet: Gold nanoparticles and quantum dots have been used for virus detection by FRET, as electron acceptor or donor respectively in FRET pairs. The fluorophore conjugated to specific antibodies undergoes a conformational change when binding to the virus, which changes the distance between the fluorescent molecules or the fluorescent/quencher molecules and a measurable change in the resonance energy transfer is observed. They have been applied to Porcin.....
Document: Gold nanoparticles and quantum dots have been used for virus detection by FRET, as electron acceptor or donor respectively in FRET pairs. The fluorophore conjugated to specific antibodies undergoes a conformational change when binding to the virus, which changes the distance between the fluorescent molecules or the fluorescent/quencher molecules and a measurable change in the resonance energy transfer is observed. They have been applied to Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) but could be used for other viruses by including the appropriate antibody [111] .
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