Selected article for: "host infection immune response and immune response"
Author: Jiang, Yuting; Zhao, Guangyu; Song, Nianping; Li, Pei; Chen, Yuehong; Guo, Yan; Li, Junfeng; Du, Lanying; Jiang, Shibo; Guo, Renfeng; Sun, Shihui; Zhou, Yusen
Title: Blockade of the C5a–C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV
  • Document date: 2018_4_24
    • ID: 0kihygau_43
    Snippet: In summary, our study demonstrated that MERS-CoV infection can result in a dysregulated host immune response, which then contributes to the severe outcomes observed after infection. However, blockade of the C5a-C5aR interaction could alleviate tissue damage induced by MERS-CoV infection through the regulation of the host immune response, especially the apoptosis and regeneration of T cells in spleens. Our study suggests a new effective clinical i.....
    Document: In summary, our study demonstrated that MERS-CoV infection can result in a dysregulated host immune response, which then contributes to the severe outcomes observed after infection. However, blockade of the C5a-C5aR interaction could alleviate tissue damage induced by MERS-CoV infection through the regulation of the host immune response, especially the apoptosis and regeneration of T cells in spleens. Our study suggests a new effective clinical intervention and adjunctive treatment for MERS-CoV infection.

    Search related documents:
    Co phrase search for related documents
    • adjunctive treatment and effective clinical intervention: 1, 2
    • adjunctive treatment and host immune response: 1, 2, 3, 4
    • adjunctive treatment and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • adjunctive treatment and MERS cov: 1, 2, 3
    • adjunctive treatment and MERS cov infection: 1, 2
    • adjunctive treatment and regeneration apoptosis: 1
    • adjunctive treatment and severe outcome: 1, 2, 3
    • adjunctive treatment effective clinical intervention and clinical intervention: 1
    • adjunctive treatment effective clinical intervention and effective clinical intervention: 1
    • adjunctive treatment effective clinical intervention and host immune response: 1
    • adjunctive treatment effective clinical intervention and immune response: 1
    • clinical intervention and effective clinical intervention: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
    • clinical intervention and host immune response: 1, 2
    • clinical intervention and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • clinical intervention and infection observe: 1
    • clinical intervention and MERS cov: 1, 2, 3
    • clinical intervention and MERS cov infection: 1
    • clinical intervention and regeneration apoptosis: 1
    • clinical intervention and severe outcome: 1, 2