Selected article for: "accelerated disease progression and HCV infection"
Author: Hsu, Shih-Hsien; Yeh, Ming-Lun; Wang, Shen-Nien
Title: New Insights in Recurrent HCV Infection after Liver Transplantation
  • Document date: 2013_4_23
    • ID: 0hbeso65_3
    Snippet: To date, the absence of preventive strategy for HCV reinfection after transplant is a major challenge for the HCV recipients undergoing LT. As mentioned above, reinfection of the liver graft is universal and characterized by accelerated progression of liver disease. Furthermore, treatment of recurrent HCV infection after LT is compromised by enhanced adverse effects and limited efficacy of interferon-based therapies. In addition, poor outcome aft.....
    Document: To date, the absence of preventive strategy for HCV reinfection after transplant is a major challenge for the HCV recipients undergoing LT. As mentioned above, reinfection of the liver graft is universal and characterized by accelerated progression of liver disease. Furthermore, treatment of recurrent HCV infection after LT is compromised by enhanced adverse effects and limited efficacy of interferon-based therapies. In addition, poor outcome after graft reinfection of HCV has increasingly become a major problem faced by the hepatologists and transplant surgeons. Thus, novel preventive and therapeutic strategies of HCV reinfection are urgently needed.

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