Neurologic Alterations Due to Respiratory Virus Infections

Bohmwald, Karen; Gálvez, Nicolás M. S.; Ríos, Mariana; Kalergis, Alexis M.

As described so far, CoVs are respiratory viruses that exhibit neurotropic capacities that not only allows them to achieve latency and avoid the immune response of the host, but also have neurological implications that can complicate the disease associated to its infection. Although their mechanisms and routes to reach the CNS have not been elicited yet, the detection of either viral proteins or genetic material in this issue has been confirmed thoroughly, branching the researcher's goals into acquiring new insights regarding this topic. So far, epidemiological reports have allowed to achieve this, but further work in animal models is required to fully comprehend the mechanisms that CoV uses to reach CNS and to achieve more suitable treatments to resolve this viral infection without an exacerbated disease.