Neurologic Alterations Due to Respiratory Virus Infections

Bohmwald, Karen; Gálvez, Nicolás M. S.; Ríos, Mariana; Kalergis, Alexis M.

On the same line, the year 2012 the first report associated with the hMPV genetic material in CSF was published (Sánchez Fernández et al., 2012 ). Sánchez Fernández et al. (2012 confirmed this detection through PCR-in a 10-year-old girl with signs of acute encephalitis-and then characterized the evolution of the disease and also included neuroimaging features therein. Detection of other etiological agents, such as herpes virus and adenovirus, were negative. Magnetic resonance imaging (MRI) showed signs of acute encephalitis and demyelinating process mainly in the temporal and occipital lobes, but these lesions eventually spread to frontal and parietal lobes (Sánchez Fernández et al., 2012) . Eventually, thanks to the treatment received, clinical improvement was noted and-35 days post hospitalization-she was discharged home, unlike many other cases, where these symptoms resulted in the death of the child (Sánchez Fernández et al., 2012) . However, some of the sequelae registered include inappropriate social abilities and infantile behavior, with severe attention-but no motor or memory-deficits (Sánchez Fernández et al., 2012) .