Author: Dai, Xiaofeng; Hakizimana, Olivier; Zhang, Xuanhao; Kaushik, Aman Chandra; Zhang, Jianying
Title: Orchestrated efforts on host network hijacking: Processes governing virus replication Document date: 2020_2_12
ID: 1dc46btc_15
Snippet: Apoptosis at the late stage of the viral life cycle avails the egress of some viruses by adopting a tolerogenic type of cell death and subverting host's immune response [54] (Figure 2 ). Accordingly, many viruses develop strategies to promote apoptosis whenever favorable. Parvovirus infection induces apoptosis via provoking DNA damage and G2/M-phase cell cycle arrest, allowing viral release with less immune response as compared with cell lysis (F.....
Document: Apoptosis at the late stage of the viral life cycle avails the egress of some viruses by adopting a tolerogenic type of cell death and subverting host's immune response [54] (Figure 2 ). Accordingly, many viruses develop strategies to promote apoptosis whenever favorable. Parvovirus infection induces apoptosis via provoking DNA damage and G2/M-phase cell cycle arrest, allowing viral release with less immune response as compared with cell lysis (Figure 2 ) [55] . Some parvoviruses such as Dependovirus use caspase activity to facilitate replication [56] .
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