Author: Lauck, Michael; Hyeroba, David; Tumukunde, Alex; Weny, Geoffrey; Lank, Simon M.; Chapman, Colin A.; O'Connor, David H.; Friedrich, Thomas C.; Goldberg, Tony L.
Title: Novel, Divergent Simian Hemorrhagic Fever Viruses in a Wild Ugandan Red Colobus Monkey Discovered Using Direct Pyrosequencing Document date: 2011_4_22
ID: 0mtmodmo_19
Snippet: Using direct pyrosequencing, we have demonstrated infection of a male red colobus monkey from Kibale National Park, Uganda, with two novel SHFV variants. To our knowledge, this is the first report of SHFV in a wild primate. These new viruses, SHFV-krc1 and SHFV-krc2, are highly divergent from each other and from the type strain (approximately 52% nucleotide sequence identity among the three variants). Both new viruses nevertheless contain homolog.....
Document: Using direct pyrosequencing, we have demonstrated infection of a male red colobus monkey from Kibale National Park, Uganda, with two novel SHFV variants. To our knowledge, this is the first report of SHFV in a wild primate. These new viruses, SHFV-krc1 and SHFV-krc2, are highly divergent from each other and from the type strain (approximately 52% nucleotide sequence identity among the three variants). Both new viruses nevertheless contain homologs of the type strain SHFV ORFs 2a, 2b, and 3 in the same genomic positions.
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