Author: Yuan, Chen; Zhang, En; Huang, Lulu; Wang, Jialu; Yang, Qian
Title: Oral administration of inactivated porcine epidemic diarrhea virus activate DCs in porcine Peyer’s patches Document date: 2018_8_16
ID: 184kmuiy_3
Snippet: Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea (PED), an acute and highly contagious enteric viral disease. PEDV infects epithelia in both small and large intestine and cause diarrhea, dehydration, and a high mortality in piglets [8] [9] [10] . Currently, PED is globally recognized as an emerging and reemerging disease that has resulted in great economic losses to the swine industry worldwide. PEDV infe.....
Document: Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea (PED), an acute and highly contagious enteric viral disease. PEDV infects epithelia in both small and large intestine and cause diarrhea, dehydration, and a high mortality in piglets [8] [9] [10] . Currently, PED is globally recognized as an emerging and reemerging disease that has resulted in great economic losses to the swine industry worldwide. PEDV infect piglets mainly through fecal-oral route (digestive tract). Vaccination is a potent tool in the control and prevention of PED [11] . It is important to develop oral vaccines that can elicit effective mucosal immune responses against PEDV infection. Oral vaccines could cut off the route of PEDV invasion. Oral administration of vaccine in pigs have been successfully used to prevent infectious disease [12, 13] .
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