Author: Dai, Xiaofeng; Hakizimana, Olivier; Zhang, Xuanhao; Kaushik, Aman Chandra; Zhang, Jianying
Title: Orchestrated efforts on host network hijacking: Processes governing virus replication Document date: 2020_2_12
ID: 1dc46btc_17
Snippet: Apoptosis is dynamically reprogrammed to facilitate viral replication. Many viruses initially inhibit cell apoptosis and induce it at a later stage ( Figure 2 ). For instance, rotavirus suppresses apoptosis via viral protein NSP1 to boost virus growth [60] , and induces late apoptosis in some cell types via disrupting mitochondrial membrane potential and releasing cytochrome C to minimize the host immune response [61] ......
Document: Apoptosis is dynamically reprogrammed to facilitate viral replication. Many viruses initially inhibit cell apoptosis and induce it at a later stage ( Figure 2 ). For instance, rotavirus suppresses apoptosis via viral protein NSP1 to boost virus growth [60] , and induces late apoptosis in some cell types via disrupting mitochondrial membrane potential and releasing cytochrome C to minimize the host immune response [61] .
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