Passive immunization does not provide protection against experimental infection with Mycoplasma haemofelis

Sugiarto, Sarah; Spiri, Andrea M.; Riond, Barbara; Novacco, Marilisa; Oestmann, Angelina; de Miranda, Luisa H. Monteiro; Meli, Marina L.; Boretti, Felicitas S.; Hofmann-Lehmann, Regina; Willi, Barbara

higher in group A compared to group B during the study period, but significance was not achieved. The eosinophils showed a similar pattern to the lymphocyte counts in cats in group A, but the decrease in cell counts was delayed, and the nadir was reached at 6 weeks pi (p F < 0.0001, Figure 5B ); again, this pattern was less pronounced in cats in group B (p F = 0.0067, Figure 5B ). In contrast, the monocyte counts increased after infection in cats in group A, with maximal values reached at day 35 pi (p F < 0.0001, Figure 5C ); again, this pattern was less pronounced in cats in group B (p F = 0.0135, Figure 5C ). When compared to the counts in group B, the monocyte counts in group A were higher at most of the time points pi, with significance reached at days 3, 21, 35, and 100 pi (p MWU < 0.05, Figure 5C ). The monocyte cell counts were higher in group A compared to group B at most time points pi when cat JHW3 was excluded, with significance reached at days 3 and 21 pi (P MWU < 0.05). The neutrophils significantly changed over time only in cats in group A (p F = 0.0007, Figure 5D ). There were no significant differences in the neutrophil counts between the two groups.