Author: Le-Viet, Nhiem; Le, Viet-Nho; Chung, Hai; Phan, Duc-Tuan; Phan, Quang-Duong; Cao, Thanh-Van; Abat, Cédric; Raoult, Didier; Parola, Philippe
Title: Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam Document date: 2019_3_4
ID: 0uwm4dk9_39
Snippet: Similar to some previous studies in Southeast Asia, our study illustrates that influenza is a major cause (20.9%) of AUF [7, 49, 50] . None of the 384 throat swabs from Controls were positive for influenza, even though afebrile patients may carry the virus [7] . Although influenza is reputedly linked to cold weather in temperate regions [51] , it occurs throughout the year in tropical regions such as Vietnam [50] . Because of the high proportion .....
Document: Similar to some previous studies in Southeast Asia, our study illustrates that influenza is a major cause (20.9%) of AUF [7, 49, 50] . None of the 384 throat swabs from Controls were positive for influenza, even though afebrile patients may carry the virus [7] . Although influenza is reputedly linked to cold weather in temperate regions [51] , it occurs throughout the year in tropical regions such as Vietnam [50] . Because of the high proportion of coinfection with influenza virus and bacteria observed in this study (Table 5) , antibiotics might be considered in several cases, particularly in elderly or risk-associated patients, because the majority of influenza-related deaths are caused by bacterial superinfection [52] . An influenza vaccination programme should be discussed for the local population in Vietnam, at least for the populations at high risk for severe influenza, including pregnant women, children aged <5 years, the elderly, and individuals with underlying health conditions [53] .
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