Selected article for: "chain reaction and high sensitivity"

Author: Vittucci, Anna Chiara; Spuri Vennarucci, Valentina; Grandin, Annalisa; Russo, Cristina; Lancella, Laura; Tozzi, Albero Eugenio; Bartuli, Andrea; Villani, Alberto
Title: Pertussis in infants: an underestimated disease
  • Document date: 2016_8_15
  • ID: 10xqdm7m_13
    Snippet: The Real Time-Polymerase Chain Reaction (RT-PCR) targeting IS481 is the most commonly used diagnostic tool when suspecting pertussis given its high sensitivity since up to 238 copies of IS481 is found in the BP genome. The high sensitivity does not correspond to high specificity, as few copies of IS481 are also present in the genome of Bordetella holmesii and Bordetella bronchiseptica [16] ......
    Document: The Real Time-Polymerase Chain Reaction (RT-PCR) targeting IS481 is the most commonly used diagnostic tool when suspecting pertussis given its high sensitivity since up to 238 copies of IS481 is found in the BP genome. The high sensitivity does not correspond to high specificity, as few copies of IS481 are also present in the genome of Bordetella holmesii and Bordetella bronchiseptica [16] .

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