Selected article for: "mRNA expression and TNF mRNA expression"
Author: Pinheiro, Aruanã Joaquim Matheus Costa Rodrigues; Gonçalves, Jaciara Sá; Dourado, Ádylla Wilenna Alves; de Sousa, Eduardo Martins; Brito, Natilene Mesquita; Silva, Lanna Karinny; Batista, Marisa Cristina Aranha; de Sá, Joicy Cortez; Monteiro, Cinara Regina Aragão Vieira; Fernandes, Elizabeth Soares; Monteiro-Neto, Valério; Campbell, Lee Ann; Zago, Patrícia Maria Wiziack; Lima-Neto, Lidio Gonçalves
Title: Punica granatum L. Leaf Extract Attenuates Lung Inflammation in Mice with Acute Lung Injury
  • Document date: 2018_2_20
    • ID: 0e9lq1b5_27
    Snippet: Reduces TNF-α and IL-1β but Not IL-6 mRNA Expression in the Lungs. LPS instillation significantly increased TNF-α, IL-1β, and IL-6 mRNA expression in the lungs (Figures 4(a)-4(c) ). When tested at 30 mg/kg, EAFPg did not affect TNF-α, IL-1β, and IL-6 mRNA expression. On the other hand, 100 and 300 mg/kg EAFPG significantly downregulated lung TNF-α and IL-1β but not IL-6 expression in mice with ALI. Likewise, dexamethasone treatment signif.....
    Document: Reduces TNF-α and IL-1β but Not IL-6 mRNA Expression in the Lungs. LPS instillation significantly increased TNF-α, IL-1β, and IL-6 mRNA expression in the lungs (Figures 4(a)-4(c) ). When tested at 30 mg/kg, EAFPg did not affect TNF-α, IL-1β, and IL-6 mRNA expression. On the other hand, 100 and 300 mg/kg EAFPG significantly downregulated lung TNF-α and IL-1β but not IL-6 expression in mice with ALI. Likewise, dexamethasone treatment significantly inhibited the expression of all evaluated cytokines, and the effects of the dexamethasone were significantly higher than those observed for EAFPg.

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