Selected article for: "biological system and system biology"

Author: Hu, Le-Le; Chen, Chen; Huang, Tao; Cai, Yu-Dong; Chou, Kuo-Chen
Title: Predicting Biological Functions of Compounds Based on Chemical-Chemical Interactions
  • Document date: 2011_12_29
  • ID: 0mn1gbll_39_1
    Snippet: ed Abstracts, such as polyethylene [50] , 1-aminocyclopropane-1-carboxylic acid [51] , cyclopropanecarboxylic acid [52] , 3-hydroxyphenylacetic acid [53] , and acetophenone [54] . In Table 4 , most of the interactive compounds of cyclopropylamine belong to the 11 th metabolic pathway classes. According to above analysis, cyclopropylamine is suggested to participate in the Xenobiotics Biodegradation Metabolism, which was the 1 st -order predicted .....
    Document: ed Abstracts, such as polyethylene [50] , 1-aminocyclopropane-1-carboxylic acid [51] , cyclopropanecarboxylic acid [52] , 3-hydroxyphenylacetic acid [53] , and acetophenone [54] . In Table 4 , most of the interactive compounds of cyclopropylamine belong to the 11 th metabolic pathway classes. According to above analysis, cyclopropylamine is suggested to participate in the Xenobiotics Biodegradation Metabolism, which was the 1 st -order predicted class for cyclopropylamine by our method. Accordingly, it is quite reasonable to expect that our method may provide useful information for further investigating into biological functions of compounds from the viewpoint of system biology.

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