Author: Muñoz-González, Sara; Ruggli, Nicolas; Rosell, Rosa; Pérez, Lester Josué; Frías-Leuporeau, Maria Teresa; Fraile, Lorenzo; Montoya, Maria; Cordoba, Lorena; Domingo, Mariano; Ehrensperger, Felix; Summerfield, Artur; Ganges, Llilianne
Title: Postnatal Persistent Infection with Classical Swine Fever Virus and Its Immunological Implications Document date: 2015_5_4
ID: 13cii3on_39_1
Snippet: petent piglets was remarkable, and it might have been due to the low levels in the neutralising antibody titres detected from the fourth to the sixth weeks post-infection. Previous studies have shown that vaccine-challenged pigs that were not fully protected were CSFV positive in the tonsils after viral challenge, despite having some neutralising antibody response [7, [54] [55] [56] . In contrast, the constant exposure of the immunocompetent pigl.....
Document: petent piglets was remarkable, and it might have been due to the low levels in the neutralising antibody titres detected from the fourth to the sixth weeks post-infection. Previous studies have shown that vaccine-challenged pigs that were not fully protected were CSFV positive in the tonsils after viral challenge, despite having some neutralising antibody response [7, [54] [55] [56] . In contrast, the constant exposure of the immunocompetent piglets to the virus from the remainder of the infected litter likely influenced the neutralising antibodies' consumption, thus avoiding the anamnestic effect of the humoral response [57] .
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