Author: Muñoz-González, Sara; Ruggli, Nicolas; Rosell, Rosa; Pérez, Lester Josué; Frías-Leuporeau, Maria Teresa; Fraile, Lorenzo; Montoya, Maria; Cordoba, Lorena; Domingo, Mariano; Ehrensperger, Felix; Summerfield, Artur; Ganges, Llilianne
Title: Postnatal Persistent Infection with Classical Swine Fever Virus and Its Immunological Implications Document date: 2015_5_4
ID: 13cii3on_44
Snippet: Interestingly, the percentage of CD172a+/SLAII+ cells found in the BMHCs from persistent infected piglets was increased by 20% over the value found in naive pigs. Previous studies with the CSF acute form have shown that, after severe immunosuppression, SLAII+ cell populations decreased considerably [71] . Similarly, immature granulocytes, specifically 6D10+ cells [72] , were the predominant cell population in these pigs, similar to the cellular p.....
Document: Interestingly, the percentage of CD172a+/SLAII+ cells found in the BMHCs from persistent infected piglets was increased by 20% over the value found in naive pigs. Previous studies with the CSF acute form have shown that, after severe immunosuppression, SLAII+ cell populations decreased considerably [71] . Similarly, immature granulocytes, specifically 6D10+ cells [72] , were the predominant cell population in these pigs, similar to the cellular profiles found after the CSF acute form [46, 71] . These cells were infected with a high concentration of viral RNA, promoting virus spread in the persistently infected animals.
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