Prevalence and genetic diversity analysis of human coronaviruses among cross-border children

Liu, Peilin; Shi, Lei; Zhang, Wei; He, Jianan; Liu, Chunxiao; Zhao, Chunzhong; Kong, Siu Kai; Loo, Jacky Fong Chuen; Gu, Dayong; Hu, Longfei

Males and females shared a common detection rate of all the HCoVs studied and no significant difference was found among the detection rate of the four strains. Also, the p values of Fisher's chi-square test showed no significant difference in detection rates among different origins. The first three clinical symptoms of HCoVs infection were fever (p = 0.08), throat congestion (p = 0.58) and antiadoncus (p = 0.09). Yet, there was no significant difference between HCoVs infected and noninfected patients. For the age group distribution of four HCoVs infections, the infant age group (<1 year old) with weaker respiratory immunity was showed with the highest infection rate in total types of HCoVs infection (p = 0.049) and OC43 infection (p = 0.068) (Fig. 1b) .