Selected article for: "human protein and mRNA expression"

Author: Zhao, Bing; Chen, Ye-Guang
Title: Regulation of TGF-ß Signal Transduction
  • Document date: 2014_9_23
  • ID: 1ag9mnd2_17
    Snippet: Other mechanisms may be also employed to control their transcription. In search for miRNAs interfering type I receptor expression, we found that microRNA miR-24 reduces the mRNA and protein levels of human activin type I receptor ALK4 (ALK4) by targeting the 3 -untranslated region of ALK4 mRNA and inhibits activin signaling [88] . Consequently, miR-24 represses the activin-mediated erythroid differentiation of K562 cells, erythroid colony formati.....
    Document: Other mechanisms may be also employed to control their transcription. In search for miRNAs interfering type I receptor expression, we found that microRNA miR-24 reduces the mRNA and protein levels of human activin type I receptor ALK4 (ALK4) by targeting the 3 -untranslated region of ALK4 mRNA and inhibits activin signaling [88] . Consequently, miR-24 represses the activin-mediated erythroid differentiation of K562 cells, erythroid colony formation, and maturation of human CD34+ hematopoietic progenitor cells. T RII expression is also repressed by mir-106b [89] .

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