Author: Girsch, James H.; Walters, Katherine; Jackson, Wallen; Grose, Charles
Title: Progeny Varicella-Zoster Virus Capsids Exit the Nucleus but Never Undergo Secondary Envelopment during Autophagic Flux Inhibition by Bafilomycin A1 Document date: 2019_8_13
ID: 1qbklvqy_11
Snippet: As another control, we reexamined the 932 transmission electron micrographs in our archives and selected 24 that were taken of infected cells at 24 hpi. Because of the low titer of input VZV, newly infected monolayers did not show cytopathic effect until around 36 to 48 hpi. Also because of the low titer of input virus, virus entering a cell could not be easily detected by transmission electron microscopy (TEM) at the plasma membrane or at the nu.....
Document: As another control, we reexamined the 932 transmission electron micrographs in our archives and selected 24 that were taken of infected cells at 24 hpi. Because of the low titer of input VZV, newly infected monolayers did not show cytopathic effect until around 36 to 48 hpi. Also because of the low titer of input virus, virus entering a cell could not be easily detected by transmission electron microscopy (TEM) at the plasma membrane or at the nuclear membrane during the first 24 hpi (see Fig. S3 in the supplemental material). Thus, the viral particles within the nuclear membrane shown in Fig. 4
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